Genetic buffering capacity - The strength of interaction between a gene, or genetic module, and a particular perturbation. Strong interactions indicate genes with high buffering capacity, meaning that the gene activity is required for phenotypic stability in response to even weak intensity of perturbation .
Genetic buffering selectivity - The qualitative pattern of interactions for a gene or genetic module, where gene interaction is measured in the context of different perturbation types .
Genetic buffering specificity - The combined buffering capacity and selectivity of a gene or genetic module. Genetic interaction modules are defined on the basis of shared genetic buffering specificity between individual genes. Hierarchical clustering of quantitative interaction data is presented as one strategy for depicting genetic buffering specificity and identifying genetic interaction modules.
Genetic buffering protocol - The organization of genetic buffering modules and their molecular activities that confer cellular robustness in response to a perturbation. Connectivity between genetic interaction modules together with molecular genetic knowledge of the functions of genes in each module facilitates hypotheses about genetic buffering protocols.
Genetic epidemiology - The study of genetic components in complex biological system.
Genetic interaction module - A set of genes sharing the same genetic buffering specificity. Gene interaction modules are experimentally defined using knockout strains in a co-isogenic genetic background, are dynamic with respect to the perturbations and gene deletions tested, and are also dependent upon the method used for classifying genes according to their shared buffering specificity (e.g., hierarchical clustering) .
Genetic polymorphism - The difference in DNA sequence from a reference sequence.
Genistein – A chemical of the isoflavone class found in plants that has a structure similar to estrogen. Hence, it is a phytoestrogen.
Genomics - The high throughput, highly parallel study of all the genes (and gene products - RNA and proteins) as a dynamic system, over time, determining how they interact and influence biological pathways, networks, and physiology, in a global sense.
Gut microflora – All of the microbes in the gastrointestinal tract.
Haplotype – A contraction of the phrase “haploid genotype”. A specific collection of linked polymorphism (e.g., SNPs, simple tandem repeats, or insertions and deltions) within a cluster of related genes or region of a chromosome.
Haplo - sufficient - When one functional allele suffices as well as two to produce the normal phenotype.
Health disparity - Referring to gap in the quality of health or health care between ethnic/racial groups and the general population. These population-specific differences are frequently observed as increased frequency, earlier onset, greater severity, higher morbidity and/or unresponsiveness to treatment for a particular disease.
Health Information Standards Board (HISB) - A subgroup of the American National Standards Institute (ANSI). The American National Standards Institute's Healthcare Informatics Standards Board (ANSI HISB) provides an open, public forum for the voluntary coordination of healthcare informatics standards among all United States' standard developing organizations.
Health Insurance Portability and Accountability Act (HIPAA) -The Administrative Simplification provisions of the Health Insurance Portability and Accountability Act of 1996 are intended to reduce the costs and administrative burdens of health care by making possible the standardized, electronic transmission of many administrative and financial transactions that are currently carried out manually on paper. HIPAA also has some significant implications for the solicitation of participants to become research subjects in research settings.
Genetic buffering selectivity - The qualitative pattern of interactions for a gene or genetic module, where gene interaction is measured in the context of different perturbation types .
Genetic buffering specificity - The combined buffering capacity and selectivity of a gene or genetic module. Genetic interaction modules are defined on the basis of shared genetic buffering specificity between individual genes. Hierarchical clustering of quantitative interaction data is presented as one strategy for depicting genetic buffering specificity and identifying genetic interaction modules.
Genetic buffering protocol - The organization of genetic buffering modules and their molecular activities that confer cellular robustness in response to a perturbation. Connectivity between genetic interaction modules together with molecular genetic knowledge of the functions of genes in each module facilitates hypotheses about genetic buffering protocols.
Genetic epidemiology - The study of genetic components in complex biological system.
Genetic interaction module - A set of genes sharing the same genetic buffering specificity. Gene interaction modules are experimentally defined using knockout strains in a co-isogenic genetic background, are dynamic with respect to the perturbations and gene deletions tested, and are also dependent upon the method used for classifying genes according to their shared buffering specificity (e.g., hierarchical clustering) .
Genetic polymorphism - The difference in DNA sequence from a reference sequence.
Genistein – A chemical of the isoflavone class found in plants that has a structure similar to estrogen. Hence, it is a phytoestrogen.
Genomics - The high throughput, highly parallel study of all the genes (and gene products - RNA and proteins) as a dynamic system, over time, determining how they interact and influence biological pathways, networks, and physiology, in a global sense.
Gut microflora – All of the microbes in the gastrointestinal tract.
Haplotype – A contraction of the phrase “haploid genotype”. A specific collection of linked polymorphism (e.g., SNPs, simple tandem repeats, or insertions and deltions) within a cluster of related genes or region of a chromosome.
Haplo - sufficient - When one functional allele suffices as well as two to produce the normal phenotype.
Health disparity - Referring to gap in the quality of health or health care between ethnic/racial groups and the general population. These population-specific differences are frequently observed as increased frequency, earlier onset, greater severity, higher morbidity and/or unresponsiveness to treatment for a particular disease.
Health Information Standards Board (HISB) - A subgroup of the American National Standards Institute (ANSI). The American National Standards Institute's Healthcare Informatics Standards Board (ANSI HISB) provides an open, public forum for the voluntary coordination of healthcare informatics standards among all United States' standard developing organizations.
Health Insurance Portability and Accountability Act (HIPAA) -The Administrative Simplification provisions of the Health Insurance Portability and Accountability Act of 1996 are intended to reduce the costs and administrative burdens of health care by making possible the standardized, electronic transmission of many administrative and financial transactions that are currently carried out manually on paper. HIPAA also has some significant implications for the solicitation of participants to become research subjects in research settings.
Nutrigenômica Brasil- Todos os Direitos Reservados- Desenvolvido por Studio Nartes