Nutrigenomics or Nutritional Genomics
Nutritional genomics represents the study of the genome and nutrition interactions. By introducing new molecular tools in classical nutrition studies, this new integrated and multidisciplinary science aims at understanding how diet influences the genome and, consequently, health and disease, and also how genetic variation influences response to diet.
Nutrigenomics evaluates the influence of nutrients and food bioactive compounds on the structure and expression of the genome.
Nutrigenetics evaluates the influence of genetic polymorphism, mainly single nucleotide polymorphisms (SNPs), on nutritional requirements and chronic disease risk.
Research with both nutrigenomic and nutrigenetic approach will be fundamental for the establishment of personalized dietary recommendations for the reduction of chronic disease risk.
According to Kaput and Rodriguez (Physiol Genomics 16: 166–177, 2004), nutrigenomics can be best explained by 5 tenets:
- Under certain circumstances and in some individuals, diet can be a serious risk factor for a number of diseases.
- Common dietary chemicals can act on the human genome, either directly or indirectly, to alter gene expression or structure.
- The degree to which diet influences the balance between healthy and disease states may depend on an individual’s genetic makeup.
- Some diet-regulated genes (and their normal, common variants) are likely to play a role in the onset, incidence, progression, and/or severity of chronic diseases.
- Dietary intervention based on knowledge of nutritional requirement, nutritional status, and genotype (i.e., "personalized nutrition") can be used to prevent, mitigate or cure chronic disease
Nutritional genomics represents the study of the genome and nutrition interactions. By introducing new molecular tools in classical nutrition studies, this new integrated and multidisciplinary science aims at understanding how diet influences the genome and, consequently, health and disease, and also how genetic variation influences response to diet.
Nutrigenomics evaluates the influence of nutrients and food bioactive compounds on the structure and expression of the genome.
Nutrigenetics evaluates the influence of genetic polymorphism, mainly single nucleotide polymorphisms (SNPs), on nutritional requirements and chronic disease risk.
Research with both nutrigenomic and nutrigenetic approach will be fundamental for the establishment of personalized dietary recommendations for the reduction of chronic disease risk.
According to Kaput and Rodriguez (Physiol Genomics 16: 166–177, 2004), nutrigenomics can be best explained by 5 tenets:
- Under certain circumstances and in some individuals, diet can be a serious risk factor for a number of diseases.
- Common dietary chemicals can act on the human genome, either directly or indirectly, to alter gene expression or structure.
- The degree to which diet influences the balance between healthy and disease states may depend on an individual’s genetic makeup.
- Some diet-regulated genes (and their normal, common variants) are likely to play a role in the onset, incidence, progression, and/or severity of chronic diseases.
- Dietary intervention based on knowledge of nutritional requirement, nutritional status, and genotype (i.e., "personalized nutrition") can be used to prevent, mitigate or cure chronic disease
Nutrigenômica Brasil- Todos os Direitos Reservados- Desenvolvido por Studio Nartes