ICMAA– Preliminary Program


10th International Conference on Mechanisms of Antimutagenesis and Anticarcinogenesis (ICMAA  2010).


Sunday - September 26, 2010
International Workshops I

 

13:00-15:00    International Workshop I:
The Human Variome Project (HVP): An international collaboration to catalogue human genetic variation. 
Chairs: Richard Cotton, Genomic Disorders Research Centre, Melbourne, Australia
            Jim Kaput, Division of Personalized Nutrition and Medicine, FDA, USA

1. What is the Human Variome Project?
Richard Cotton Coordinator of the HVP
2. Genetic Variation and Structure of Brazilian Population related to genetic diseases
Sérgio Danilo Penna, Federal University of Minas Gerais, MG, Brazil
3. How can Brazil participate in the Human Variome Project and what is the first step?
Vera Lucia da Silva Lopes, Fac. de Ciências Médicas, Depto. Genética Médica, UNICAMP, SP, Brazil

Discussion Forum:
George Davey Smith, Clinical Epidemiology, Bristol University, UK,
Caroline Relton, Human Nutrition Research Centre, University of Newcastle, UK
Mara Hutz, Brazilian Genetic Society
Carlos Frederico Martins Menck, Brazilian Genetic Society
Salmo Raskin, Brazilian Medical Genetic Society
Lucia Regina Ribeiro, Brazilian and Latin American Nutrigenomics Organizations
Elza Sakamoto-Hojo, Brazilian Mutagen Society
Ximena Aguilar Mercado, Bolivian Nutrigenomics Organization.
Maria Eugenia Ascarrunz, Bolivian Mutagen Society
Enrique Zamorano-Ponce, Chilean Nutrigenomics and Latin American Mutagen Society
Patricia Ostrosky, Ministry of Health, Mexico
Stefano Bonassi, International Association of Environmental Mutagens Societies (IAEMS)
Takehiko Nohmi, Asian Mutagen Society (AAEMS).
Young-Joon Surh, South Korea Mutagen Society
Maturos Ruchirawat, Chulabhorn Research Institute (CRI), Bankok, Thailand

The Workshop will be open to all interested persons

19:30    Opening Ceremony

INCON/ICMAA: Similar scientific subjects with same objectives
Lucia Regina Ribeiro, State University of São Paulo, SP, Brazil

Opening Plenary Lecture ICMAA
Mechanistic approaches to the prevention of mutation and cancer
Silvio De Flora University of Genova, Italy

Opening Session

Monday, Tuesday and Wednesday - September 27, 28 and 29, 2010
Young Investigators` Session
Plenary Sessions
Symposia

Young Investigator`s Session
Chairs: David De Marini, EPA, USA
             Hanelore Daniel Technische Universität – München, Germany

Discussion Forum:
Flavia Fayet, School of Molecular and Microbial Biosciences,University of Sydney, Australia
Gaelle Fave, Human Nutrition Research Centre, University of Newcastle, UK
David Cameron Smith, School of Exercise and Nutrition, Deakin University, Melbourne, Australia
Rodrigo G Dias, Lab. of Genetics and Molecular Cardiology, Heart Instit, InCor - USP, Brazil.
Rafael Eduardo Montaño Arrieta, Universidad Mayor de Santo Andrés – UMSA, La Paz, Bolivia
Daniel Araki Ribeiro, Universidade Federal de São Paulo, UNIFESP, Brazil
Ingrid Felicidade, State University of Sao Paulo, UNESP, Brazil
Alvaro Galvez Lima, Universidad Mayor de Santo Andrés – UMSA, La Paz, Bolivia

Open to all young investigators, PhD and MSc students.

In this Session will be discussed career paths, opportunities and the future for the areas.  Some selected abstracts judged to have the most scientific merit will be invited to make an oral presentation during the Young Investigators’ session.

Plenary Sessions

1. Natural Products with Anticarcinogenic/Chemopreventive Properties
HRH Princess Chulabhorn, Chulabhorn Research Institut (CRI), Bangkok, Thailand

2. Postgenomic mechanisms in antimutagenesis and anticarcinogenesis
Alberto Izzotti, Department of Health Sciences, University of Genoa, Italy

3. Targeting Inflammatory Pathways for Prevention of Cancer by Dietary Agents and Traditional Medicine.
Bharat B. Aggarwal, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

4. Cancer prevention research
Scott Lippman, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

5. Antimutagenic and anticarcinogenic strategies applied to chemopreventive drug development at the US National Cancer Institute.
Vernon E. Steele, National Cancer Institute,Bethesda, MD, USA

6. Success and failure of epidemiology in the quest for cancer prevention
Stefano Bonassi, Clinical and Molecular Epidemiology, IRCCS San Raffaele Pisana, Roma, Italy

7. Application of transgenic rodents for antimutagenesis and anticarcinogenesis
Takehiko Nohmi, Division of Genetics and Mutagenesis National Institute of Health Sciences, Tokyo, Japan

Symposia

Symposium I: Modulation of Genotoxicity and Carcinogenicity with Chemopreventives.
Chais: Gary J. Kelloff, , National Cancer Institute, Bethesda, MD, USA 
Co-Chair:Brazilian, Latin American people

1. Biomarkers in Anticarcinogenesis and Chemoprevention
Gary J. Kelloff, National Cancer Institute, Bethesda, MD, USA 
2. Chemoprevention Trials in China with Broccoli Sprouts Beverages
Patricia Egner, Environmental Health Sciences Johns Hopkins Bloomberg School of Public Health Baltimore, USA
3. Mechanisms of inhibition of cigarette smoke genotoxicity and carcinogenicity
Roumen Balansky, National Center of Oncology, Sofia, Bulgaria
4. To be confirmed

Symposium II: Dietary Prevention Of Mutation And Cancer
Chair: Piero Dolara, University of Florence, Italy
Co-Chair: Brazilian, Latin American people
                             
1. Polyphenol containing food and cancer prevention
Piero Dolara, University of Florence, Italy
2. Diet and cancer epidemiology: The experience of EPIC
Domenico Palli, ISPO, Florence, Italy
3. Personalised prevention of DNA damage using dietary and life-style strategies
Micahel Fenech, CSIRO, Human Nutrition, Adelaide, Australia
4. Diet, mutation and cancer
Lynn Ferguson, University of Auckland, Auckland, New Zealand
5. Inhibition of Fried-Meat-Induced Colorectal DNA Damage and Altered Systemic Genotoxicity by Cruciferous Vegetables, Yogurt, and Chlorophyllin
David Demarini, Integrated Systems Toxicology Division, EPA, North Carolina, USA,

Symposium III: Epigenetic mechanisms and cancer prevention
Chair: James E. Trosko, Michigan State University, East Lansing, Michigan, USA
Co-Chair: Brazilian, Latin American people                

1. Role of Human Adult Stem Cells, Cell-Cell Communication, Nutrition/Diet on the Multi-Stage, Multi-Mechanism Process of Carcinogenesis: Pre ( Barker Hypothesis) - and Post- Natal Consequences. 
James E. Trosko, College of Human Medicine, Michigan State University, East Lansing, Michigan, USA
2. Connexins and the Chemoprevention of Prostate Câncer.
Parmender P. Mehta  
3. Gap junctional intercellular communication, a systems-biology directed in vitro bioassay for identifying anti-tumorigenic properties of cancer preventing compounds.
Brad Upham
4. Epigenetic basis of antimutagenesis and anticarcinogenesis.
Hikoya Hayatsu Faculty of Pharmaceutical Sciences, Okayama University, Tsushima, Okayama, Japan

Symposium IV: Modulation of Oxidative Stress and Inflamation-Induced Carcinogenesis and Mutagenesis
Young-Joon  Surh, South Korea (in preparation)

Symposium V: Modulation of signal transduction
Young-Joon  Surh, South Korea (in preparation)

Symposium VI: Mechanisms of modulation of angiogenesis, invasion, and metastasis
Adriana Albini, Italy (in preparation)

Symposium VII: The Archeology of Cancer Prevention
Chair:  David J. Waters, Professor and Associate Director, Purdue University Center on Aging and the Life Course

“The purpose of the symposium is to examine closely what we have learned from large-scale cancer prevention trials that have reported null results.  It will be shown that some fresh digging at these old locations can yield valuable new insights into framing the critical yet-to-be-answered questions, and for guiding future investigative approaches”.   
1. Beyond Finasteride: 5 Alpha Reductase Inhibitors for Prostate Cancer Prevention.
David G. Bostwick, Bostwick Laboratories, Richmond, VA USA 
2. Lessons from Beta-Carotene and Lung Cancer Prevention Trials
Susan Mayne, Division Head of Chronic Disease Epidemiology, Yale University, New Haven, CT USA
3. Selenium and Cancer Prevention in a Post-SELECT World
David J. Waters, Professor and Associate Director, Purdue Center on Aging and the Life
Course; Director, Gerald P. Murphy Cancer Foundation, W. Lafayette, IN USA
PANEL DISCUSSION (3 Speakers)

18:00 Discussion, summing up and report ” led by Chairs and Co-Chairs of all Sessions.
Main Chair: Delbert M. Shankel, Professor of Microbiology and Chancellor Emeritus

Wednesday - September 29, 2010
Closing Ceremony

19:00   Closing Plenary Lecture - INCON/ICMAA:  Combining scientific knowledge on environment-gene interaction to optimize human health
Michael Fenech, CSIRO, Adelaide, Australia
0:00   Closing Session